Nutrition & Supplements

Magnesium for Bone Health: The Form Matters More Than You Think

Magnesium is calcium's essential partner โ€” without enough magnesium, calcium can't properly integrate into bone matrix, and Vitamin D can't function optimally either. Most Canadians don't get enough. But the supplement market is full of magnesium products that barely absorb, and the r/Supplements community has this right: magnesium oxide is largely a waste of money.

Why Magnesium Matters for Bones

About 60% of the body's magnesium is stored in bone. It plays several roles in bone health:

Several observational studies have found associations between higher dietary magnesium intake and better bone density in older adults. Whether supplementing magnesium in people who aren't deficient produces additional bone benefit is less clear โ€” the strongest case is for correcting deficiency, not supplementing beyond normal levels.

How Much Do You Need?

Health Canada's Dietary Reference Intakes:

GroupRecommended Daily IntakeUpper Tolerable Limit (supplements)
Adult men 19-30400 mg/day350 mg/day from supplements
Adult men 31+420 mg/day350 mg/day from supplements
Adult women 19-30310 mg/day350 mg/day from supplements
Adult women 31+320 mg/day350 mg/day from supplements
Pregnant women350-360 mg/day350 mg/day from supplements

Note: the upper limit applies to supplemental magnesium only โ€” not dietary magnesium from food. High-dose supplemental magnesium causes diarrhea, which is both unpleasant and a sign your gut isn't absorbing it anyway.

The deficiency reality: Canadian dietary surveys consistently show a significant portion of adults don't meet magnesium RDAs through diet alone, particularly older adults whose absorption decreases with age. If your diet is low in leafy greens, legumes, nuts, and seeds โ€” the main food sources โ€” supplementation is worth considering.

Magnesium Forms: What to Take and What to Skip

FormAbsorptionBest ForVerdict
Magnesium glycinateHighBone health, sleep, anxiety โ€” well toleratedโœ… Best overall
Magnesium citrateHighBone health, constipation, general supplementationโœ… Excellent choice
Magnesium malateHighMuscle fatigue, fibromyalgia symptomsโœ… Good for muscle focus
Magnesium threonateHigh (brain-specific)Cognitive function โ€” specific brain bioavailabilityโš ๏ธ Premium price, niche use
Magnesium oxideVery low (~4%)Laxative effect, cheapโŒ Skip for bone health
Magnesium chlorideModerateTopical use; oral absorption is reasonableโš ๏ธ Fine, not optimal

Magnesium oxide is the form in the cheapest supplements and many multivitamins. Its absorption rate is around 4% โ€” you excrete most of it. The r/Supplements community has reached strong consensus on this: if you're supplementing magnesium for any health reason, oxide is the wrong choice. Glycinate or citrate absorb at 30-40%+ and have comparable pricing when you calculate cost per absorbed milligram.

Glycinate vs Citrate: Which One?

Both absorb well. Glycinate tends to be gentler on the digestive system and is often recommended for people who experience loose stools with citrate. Citrate has a mild laxative effect even at normal doses in some people โ€” useful if you're constipated, not if you're not.

For pure bone health focus, either works. Many people find glycinate better tolerated before bed, since the glycine component has mild calming properties.

Food Sources of Magnesium

Food-first is always the right approach. The best dietary sources of magnesium:

A diet that regularly includes nuts, seeds, legumes, and leafy greens will come close to meeting magnesium needs. The people most likely to fall short: those eating primarily processed foods, low-carb/keto diets that eliminate legumes and grains, and older adults with reduced absorption.

Timing and What to Take It With

Magnesium is best taken with food โ€” it absorbs better and is less likely to cause digestive issues. Avoid taking it at the same time as calcium supplements if you're taking both: calcium and magnesium compete for the same intestinal transport. Separate them by 2 hours.

Evening is a popular timing choice, not just for the absorption benefit but because magnesium glycinate in particular seems to support sleep quality in some people โ€” reasonable to take advantage of if bone health is your primary goal.

Medications that interact with magnesium: Magnesium can affect absorption of certain antibiotics (tetracyclines, quinolones), bisphosphonates (osteoporosis medications like Fosamax), and some blood pressure medications. If you take any of these, space magnesium supplementation by at least 2 hours, or confirm timing with your pharmacist.

Key Takeaways

Medical Disclaimer: This article is for educational purposes only. Consult your doctor or pharmacist before starting magnesium supplements, especially if you take medications or have kidney disease (impaired kidneys cannot excrete excess magnesium efficiently).